Food Restriction Differentially Affects Pituitary Hormone mRNAs throughout the Adult Life Span of Male F344 Rats

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Food restriction differentially affects pituitary hormone mRNAs throughout the adult life span of male F344 rats.

Because neuroendocrine mechanisms may contribute to the antiaging effects of food restriction (FR), we measured the effect of FR on mRNAs encoding anterior pituitary (AP) tropic hormones. Slot blots or RNase protection assays were done on AP RNA from 3-, 6-, 12-, 18- and 24-mo-old male F344 rats consuming food ad libitum (AL) or food restricted (FR; to 60% of AL food intake) from 6 wk. Both AL ...

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ژورنال

عنوان ژورنال: The Journal of Nutrition

سال: 2001

ISSN: 0022-3166,1541-6100

DOI: 10.1093/jn/131.6.1687